INVOLVEMENT OF CATALASE IN SACCHAROMYCES CEREVISIAE HORMETIC RESPONSE TO HYDROGEN PEROXIDE

Ruslana Vasylkovska, Nadia Burdylyuk, Halyna Semchyshyn

Abstract


In this study, we investigated the relationship between catalase activity and H2O2-induced hormetic response in budding yeast S. cerevisiae. In general, our data suggest that: (i) hydrogen peroxide induces hormesis in a concentration- and time-dependent manner; and (ii) the effect of hydrogen peroxide on yeast colony growth positively correlates with the activity of catalase that suggests the enzyme involvement in overall H2O2-induced stress response and hormetic response in yeast.

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